lithium diisopropylamide in a sentence

1. Deprotonation of DMSO requires strong bases like lithium diisopropylamide and sodium hydride.
2. Lithium diisopropylamide is a popular non-nucleophilic base used in organic synthesis.
3. Deprotonation with lithium diisopropylamide and addition of an alkyl halide affords the alkylated product.
4. In the presence of triethylamine and lithium diisopropylamide, enolisable aldehydes, ketones and esters are converted to trimethylsilyl enol ethers.
5. It is best known as its lithium derivative of its conjugate base, lithium diisopropylamide, known as " LDA ".
6. It's difficult to find lithium diisopropylamide in a sentence.
7. Reaction of " N "-protected indoles with butyl lithium or lithium diisopropylamide results in lithiation exclusively at the C2 position.
8. In step one the phosphine oxide is deprotonated at & minus; 90 癈 in ether with lithium diisopropylamide, then the aldehyde is added.
9. Another approach to organic reactions is by type of organic reagent, many of them bases such as lithium diisopropylamide and acids such as sulfuric acid.
10. In mixed Claisen condensations, a non-nucleophilic base such as lithium diisopropylamide, or LDA, may be used, since only one compound is enolizable.
11. If, on the other hand, lithium diisopropylamide ( LDA ) is used as the base, all of the acetone will deprotonated, making enolate ion quantitatively.
12. If, however, a more powerful base such as sodium hydride ( NaH ) or lithium diisopropylamide ( LDA ) is used, a carbonyl compound can be completely converted into its enolate ion.
13. Its synthesis ( a variation of the Ferrario reaction ) is based on deprotonation of a tetrathiophene with lithium diisopropylamide followed by reaction with elemental sulfur to a sulfur-substituted intermediate followed by vacuum pyrolysis.
14. The hydrazone is then deprotonated on the ?-carbon position by a strong base, such as lithium diisopropylamide ( LDA ), leading to the formation of a resonance stabilized anion-an azaenolate.
15. Lithium diisopropylamide ( LDA ), which is easily prepared by reaction of the strong base butyllithium with diisopropylamine, is widely used in the laboratory as a base for preparing enolate ions from carbonyl compounds.
16. The reaction of the benzothiazole sulfone ( 1 ) with lithium diisopropylamide ( LDA ) gives a metallated benzothiazolyl sulfone, which reacts quickly with aldehydes ( or ketones ) to give an alkoxide intermediate ( 2 ).
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